Publications

Guideline for the Management of Acute and Chronic Pain in Sickle-Cell Disease

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The first publication of the APS Clinical Practice Guidelines program, this guideline is the first comprehensive evidence-based guideline to address treatment of the pain of sickle-cell disease.

Authors

Lennette J. Benjamin, MD

Albert Einstein College of Medicine, Bronx, NY

Carlton D. Dampier, MD

Marion Anderson Sickle Cell Center, Philadelphia

Ada Jacox, PhD RN

Wayne State University College of Nursing, Detroit

Victoria Odesina, MS RN

St. Francis Hospital, Hartford, CT

David Phoenix, PhD

Appalachia State University, Boone, NC

Barbara S. Shapiro, MD

Univ of Pennsylvania School of Medicine, Philadelphia

Maureen Strafford, MD

New England Medical Center, Boston

Marsha Treadwell, PhD

Children's Hospital Medical Center, Oakland, CA

Contents

Overview of Sickle-Cell Disease and Related Pain
Types and Characteristics of Pain Associated with Sickle-Cell Disease
Pain Assessment
Treatment of Pain in Sickle-Cell Disease
Pharmacological Management of Sickle Pain
Acetaminophen and NSAIDs
Opioids: Side Effects, Tolerance, Physical Dependence and Addiction
Drugs
Management of an Episode of Acute Pain
Details of Opioid Administration
Psychological, Behavioral, and Physical Interventions
Importance of Comprehensive Care
Sickle Pain in Developmental Stages
Focus of Care in Various Settings