| September
is Pain Awareness Month. This month you will receive two issues
of E-news.
APS
Supports IASP Global Awareness Initiative on Pain in Older Adults
Among
the pain management and research communities, it's well known that
within the nation's growing population of older people, an estimated
50% live with persistent pain. Widespread misperceptions continue
to influence attitudes of healthcare providers and their aging patients.
For example, it's still common for providers, patients, and families
to believe pain should be accepted as an inevitable consequence
of aging. That's why this year the International Association for
the Study of Pain (IASP) and APS are collaborating on global public
and professional awareness initiatives to improve understanding
about what can and should be done to treat chronic pain in older
adults. September is Pain Awareness Month, and APS is involved in
programs with IASP and Partners for Understanding Pain to promote
improved pain care for older adults.
"The
prevalence of persistent pain climbs steadily with advancing age.
Studies show that by the seventh decade of life the rate of persistent
pain exceeds 50% in community-based samples and a whopping 80% are
in residential aged care," said Keela Herr, PhD RN, professor and
chair, adult and gerontological nursing, University of Iowa. "A
major problem is that older people think they have to live with
pain and also are worried about becoming addicted to pain medication.
This makes pain assessments in the elderly a difficult challenge
because older patients tend to under-report their pain," she added.
Herr
said pain assessments for the older population require a multifaceted,
comprehensive approach. "In older patients, we must be more comprehensive
in assessing pain, especially for those who have impaired hearing
or vision, dementia or other types of cognitive impairment," said
Herr. "These patients have difficulty communicating their pain and
usually receive fewer analgesics than others of the same age."
Herr
added that despite the high prevalence of persistent pain in older
adults, the overwhelming majority of pain studies continue to be
conducted in younger populations. "There is a glaring lack of scientific
data on pain management in older adults. As a result, multidisciplinary
pain programs that can be successful in many older patients are
underutilized because this group is under represented in pain studies
and clinics and receives fewer treatment options," she explained.
APS,
according to Herr, can be a highly effective advocate for improved
pain care in older adults. "We know pharmacological therapy for
persistent pain is most effective when combined with other approaches,
such as cognitive behavioral therapies, physical therapy, and exercise
regimens. However, older persons are more vulnerable since they
suffer from concurrent medical problems that can limit treatment
options with analgesics. So when formulating pain treatment plans
for older patients, clinicians must be aware of the risks posed
by concurrent medications and comorbid medical and psychosocial
problems," Herr explained.
To
achieve meaningful progress in combating pain in older adults, Herr
believes pain clinicians need more professional education programs
focused on treating this growing population. "There is an urgent
need for better professional education programs, further dedicated
research to help guide clinical practice, and better pain management
strategies to address the special needs of older patients with persistent
pain.
On
September 12, Dr. Herr represented APS during a national radio news
release to kick off the year-long effort with IASP and Partners
for Understanding Pain to improve professional and public awareness
about pain in the elderly. Please click
here to listen to Dr. Herr's radio appearance.
News
Highlights from The Journal of Pain
| New
Journal Column: Case Studies in Pain
In
2006, The Journal of Pain added a new column, "Case
Studies in Pain." This new feature is intended to provide
to readers scientific and clinical knowledge in a case study
format. Reports will describe the clinical course of an individual
with a common or complex pain syndrome, and scientists, clinicians,
and others with pertinent expertise will offer commentary."
We encourage you to submit cases for consideration. Submit
1-2 paragraphs to section editor Judith Paice at j-paice@northwestern.edu.
She will invite the appropriate respondents to provide commentary.
We also welcome letters to the editor (j-pain@uiowa.edu)
with comments regarding these cases. Two case studies have
been published to date in this column.
Click
here to read "Sickle
Cell Disease Related Pain: Crisis and Conflict," which
appeared in the July issue. |
The
following highlights summarize selected articles from the August
2006 issue (volume 7, number 8).
Peripheral
and Central Contributions to Hyperalgesia in Irritable Bowel Syndrome
Donald D. Price, QiQi Zhou, Baharak Moshiree, Michael E. Robinson
and G. Nicolas Verne, University of Florida Colleges of Medicine
and Dentistry
Irritable
bowel syndrome (IBS) is a common gastrointestinal disorder in which
patients experience chronic abdominal pain associated with alterations
in bowel patterns. The majority of IBS patients have low thresholds
for visceral pain, increased intensity of sensations, and widespread
hyperalgesia. In this study, University of Florida researchers examined
recent evidence for potential neural mechanisms that may contribute
to somatic and visceral hyperalgesia in IBS patients.
The
authors reported their evaluations of human and rat studies for
this research clearly point to a spinal mechanism consistent with
observations that IBS patients have enhanced responses to visceral
and cutaneous stimuli throughout the pain matrix of the brain. However,
they concluded it is unclear whether enhanced responses result from
a facilitating mechanism in the brain, a spinal sensitization due
to input from the rectum and/or colon, or a mechanism from the brain
to the spinal cord or gut.
The
study concluded that primary visceral and secondary cutaneous hyperalgesia
in IBS patients involve a mechanism dynamically maintained by tonic
input from abnormal receptors in the colon and /or rectum. Further
secondary hyperalgesia is likely to be at least partly related to
sensitization of spinal cord neurons and, therefore, might be similar
to other persistent pain conditions, such as fibromyalgia and complex
regional pain syndrome.
Commentary
by Emeran A. Mayer, VA Medical Center West Los Angeles
In his commentary on the article, Mayer asked if the proposed role
of abnormal tonic input to the spinal cord plays the central role
in IBS pathology, what drives this abnormal input? He also inquired
if there is a possible role for low-grade inflammatory changes in
the intestinal mucosa. Mayer concluded that the research identifies
a series of testable hypotheses that can be addressed by psychophysical
and brain-imaging studies.
Commentary
by Mickael Bouin, University of Montreal
Bouin believes the lack of a positive diagnostic test for IBS leaves
hypersensitivity as the main basis for IBS diagnosis. But is hypersensitivity
a biological marker or a condition of IBS? Also, Bouin asks if hypersensitivity
is specific to IBS or gut-specific in IBS patients. Although this
abnormality of the gut can be investigated in humans, he notes the
lack of specificity and sensitivity precludes use of this symptom
in clinical practice to make a positive diagnosis of IBS.
Prevalence
and Characteristics of Breakthrough Pain in Opioid-Treated Patients
with Noncancer Pain
Russell K. Portenoy, Daniel S. Bennett, Richard Rauck, Steven
Simon, Donald Taylor, Michael Brennan and Steven Shoemaker, from
various university medical centers and supported by a grant by Cephalon,
Inc.
Breakthrough
pain is the transitory exacerbation of pain that occurs in otherwise
controlled pain patients. It is estimated that up to 90 percent
of cancer patients with chronic pain experience breakthrough pain.
However, little is known about the prevalence and characteristics
of breakthrough pain in populations with chronic noncancer pain
treated with opioid medications. Researchers from nine different
pain centers recruited 228 patients and administered a phone questionnaire.
All patients had controlled baseline pain, and 74 percent said they
experienced severe breakthrough pain. The most common syndrome was
low-back pain.
The
authors concluded that breakthrough pain is highly prevalent and
variable in patients treated with opioids for noncancer chronic
pain. They further noted that if future studies show adverse outcomes
of breakthrough pain similar to cancer patients, clinicians will
need to assess and manage this pain in noncancer patients as well.
Sex, Gender and Age: Contributions to Laboratory
Pain Responding in Children and Adolescents
Cynthia D. Myers, Jennie C. I. Tsao, Dorie A. Glover, Su C.
Kim, Norman Kirk and Lonnie K. Zeltzer, UCLA Pediatric Pain Program,
David Geffen School of Medicine, UCLA
It
is widely believed that gender socialization influences pain responding.
Males typically are expected to withstand pain as evidence of being
masculine and females accept pain as a normal part of life and are
viewed as more willing to report pain. No published studies have
examined the role of gender socialization in pain responses exhibited
by children and adolescents. The goals of this study, therefore,
were to examine the relationship of sex, gender socialization and
age to responses to laboratory pain stimuli in healthy children
and adolescents. Two-hundred-forty healthy subjects, equally divided
by gender, participated in the study.
The
authors reported there were no significant mean differences between
girls' and boys' responses to laboratory pain. There was a trend
for girls to exhibit lower tolerance for pressure pain, however.
They concluded that the findings lend preliminary support to the
view that gender socialization contributes to variability in responses
to laboratory pain. This finding, however, does not appear to be
stable across age, types of pain stimuli, or parameters of pain
response.
Important
Information for Healthcare Providers Who Treat Patients with Pain
Upcoming Forum Dates and Locations:
November
17–18, 2006, (Anaheim Convention Center, Anaheim, CA)
December 8–9, 2006, (Donald E. Stevens Convention Center,
Rosemont, IL)
The
North American Pain Forum (NAPF) 2006, in collaboration with APS
and The Foundation for Better Health Care (FBHC), is launching an
innovative, comprehensive program dedicated to providing timely,
practical information to primary care physicians, nurse practitioners,
physician assistants, and nurses with a focus on increasing the
clinical understanding of pain. The goal of the program, which is
cochaired by Bill McCarberg, MD, and Dennis Turk, PhD, is to offer
new strategies for the clinical assessment, treatment, and successful
management of patients with acute and chronic pain, including end-of-life
pain.
The
NAPF 2006 forums have a unique format. They offer attendees the
opportunity to learn from eight plenary sessions and participate
in eight interactive workshops during the 2-day program. The forums
provide 15 hours of CME content to meet the AB487 Requirement for
Califorinia-Licensed Physicians.
In
addition to the comprehensive educational forums that provide evidence-based
findings on the latest advances in assessing and managing patients
with pain, other CME components of the NAPF '06 program include:
-
A dedicated NAPF Web site, www.napainforum.org
-
A monograph series consisting of three disease-state monographs
- WebRounds™
offering interactive Web conferences with online slide presentations
that participants can download
-
FBHC Interactive Clinical Encounters (ICE™)—an interactive
CD-ROM that allows participants to measure their own clinical
decision-making ability using their knowledge and skills in diagnostic,
treatment, and patient-communications domains
Visit
NAPF online at www.napainforum.org
to register.
NIH
Funding Announcement: Mechanisms, Models, Measurement, & Management
in Pain Research (R01,R21,R03)
This
funding opportunity, issued by the National Institute of Nursing
Research (NINR), seeks to inform the scientific community of the
pain research interests of the various Institutes and Centers (ICs)
at the National Institutes of Health (NIH) and to stimulate and
foster a wide range of basic, clinical, and translational studies
on pain as they relate to the missions of these ICs.
Synergistic
studies that reach across two or more of these areas are welcomed.
Interdisciplinary and multidisciplinary research is especially encouraged.
These pain research areas also cut across ICs and programs and should
not be viewed as restricted to only one specific IC. ICs include
- Molecular
and cellular mechanisms of pain
-
Genetics of pain
- Biobehavioral
pain
-
Models of pain
- Diagnosis
and assessment of pain
-
Pain management
- Epidemiology
of pain
-
Health disparities
-
Translational pain research
New
advances are needed in every area of pain research, from the micro
perspective of molecular sciences to the macro perspective of behavioral
and social sciences. Although great strides have been made in some
areas, such as the identification of neural pathways of pain, the
experience of pain and the challenge of treatment have remained
uniquely individual and unsolved. Research to address these issues
conducted by interdisciplinary and multidisciplinary research teams
is strongly encouraged, as is research from underrepresented, minority,
disabled, or women investigators.
For
more information, visit grants1.nih.gov/grants/guide/pa-files/PA-06-544.html.
New
APS SIG: Pharmacotherapy
APS is pleased to announce the formation of its fourteenth special
interest group (SIG). This newest SIG is for any APS members who
have an interest in analgesic pharmacotherapy. Drs. David Craig,
Ken Jackson, and Scott Strassels will chair this SIG. If you are
interested in joining it, please contact Dionne Wilson at the APS
national office at 847/375-4875 or dwilson@connect2amc.com.
You may also contact the chairs directly:
Call
for Election Nominations: Coming Soon!
Are
you ready to pursue a national leadership position in APS?
Do
you demonstrate such leadership qualities as vision, strategic thinking,
motivation, and a sense of dedication to the society and its mission?
If
you answered yes to any or all of these questions, or if
this sounds like someone you know, the APS Nominating Committee
requests your election nomination. Open positions include President-Elect,
Treasurer and three Directors-at-Large,
and seven positions on the Nominating Committee.
Nominees must be active APS Regular Members, and most importantly,
want to achieve positive outcomes for the society, its members,
and those who are served by its efforts. These positions will be
elected this winter to take office at the 2007 annual meeting.
Members
will receive an invitation to nominate potential election candidates
in October. Those with active e-mail addresses will be notified
by e-mail. Those without e-mail will receive instructions by mail.
In
addition, position descriptions, a list of current board and nomination
committee members and vacancies, and the disciplinary composition
and geographic representation of the board is available on the APS
Web site. APS has worked hard to make the nomination and voting
process easy for you; your participation will make it meaningful.
Please
take advantage of this opportunity. Your participation is important.
APS
Call for 2007 Paper and Poster Abstracts
Click
here to visit the call online. Submissions are due October 27,
2006.
Update
on Palliative Care Education and Training Act
After
being unanimously passed by the New York State Legislature, the
Palliative Care Education and Training Act [AB11162, S07458A] to
improve palliative care and pain management was vetoed by Governor
Pataki.
To
read more about Compassion and Choices, the group that championed
this legislation, visit www.compassionandchoices.org.
APS
E-News Then and Now: Survey Results
APS
E-News debuted in January 2003. Earlier this year, we ran nearly
the same reader satisfaction survey that was featured in our November
2003 reader survey to compare feedback. Thank you to all who shared
their valued feedback with us.
The
questions and responses (2003 responses are in black and the 2006
responses are in red) are below.
On
a scale of 1 to 5, with 1 being "least important" and 5 being "most
important," here's how you rated the following topics that frequently
appear in APS E-News (average scores):
Summaries of The Journal of Pain articles: 4.04 /
4.09
Legislation: 3.82 / 3.89
Meeting news: 3.74 / 3.83
Organization/board news: 3.29 / 3.44
Fundraising/research opportunities: 3.32 /
3.39
News about individual APS members: 2.65 /
3.03
News about organizations other than APS: 2.87 / 3.01
Have
you ever forwarded an APS E-News issue to a colleague?
Yes: 37% / 35%
No: 63% / 65%
APS
E-News is transmitted monthly. This frequency is:
About right: 98% / 89%
Too frequent: 2% / 6%
What
other topics would you like to see featured in APS E-News?
Legislation related to controlled drugs
Research on complementary medicine and pain
More on CRPS
CRPS treatments
Collaborative research endeavors from multidisciplines
Funding
announcements
More information that can be shared with consumers
Talking points on issues
Research advances written in lay language
Other pertinent pain article highlights
Breaking science, new developments, and clinical trial results
In
this year's survey we also asked those who are interested to provide
their names as a way to express interest in being involved with
APS. Those names have been shared with the APS leadership and you
will be contacted as opportunities become available.
APS
E-News welcomes your comments at any time. Please send your
thoughts to dpinkston@connect2amc.com.
Errata
In
the August e-news announcement of the 2006–2007 The Mayday
Fund Fellows, the acknowledgement of the fellows who are also APS
members incorrectly did not include Steven J. Weisman, MD, who is
a long-time APS member. We regret the omission. |