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APS
Announces Recipients of the 2007 Future
Leaders in Pain Research Small Grants
The
2007 Future Leaders in Pain Research Small
Grants program awarded funding to five
researchers in the amount of $20,000 each.
To be eligible to receive the grant, applicants
must be APS members who are within 6 years
of completing their terminal degree and
have not yet been awarded major NIH or
foundation grant funding. In 2007, 20
competitive applications for funding were
received. Members of the Small Grants
Committee reviewed and scored the applications
in preparation for selection of grant
recipients.
APS
is proud to announce the following 2007
grant recipients. Recipients will attend
the Annual Scientific Meeting to report
on the progress of their research studies
to the members of the Small Grants Committee.
Anna
C. Long, PhD
Oregon Health and Science University
Portland, OR
"Web-Based Cognitive Behavioral Therapy
for Adolescents with Chronic Pain: Measuring
Functional Outcomes"

Laura A. Frey Law, PhD PT
University of Iowa
Iowa City, IA
"Individual Differences Contributing
to Muscle Pain Heterogeneity"

Jamie L. Rhudy, PhD
University of Tulsa
Tulsa, OK
"Menstrual Cycle Influences on Supraspinal
Modulation of Pain and Nociception"

Lisa C. Loram, PhD MSc
University of Colorado–Boulder
Boulder, CO
"Long Duration Reversal of Neuropathic
Pain by a Single Intrathecal Administration
of Adenosine 2a Receptor Agonists: A Novel
Therapy for Neuropathic Pain"
Magali Millecamps, PhD
McGill University
Montreal, Canada
"Animal Models of Low Back Pain"
APS
gratefully acknowledges Endo Pharmaceuticals
and Cephalon for their generous funding
of the 2007 grants program and extends
special thanks to the members of the APS
Small Grants Committee for their efforts
on behalf of the program.
APS
Small Grants Committee
Sandra Ward, PhD RN, Chair
Michael Caterina, PhD
C. Richard Chapman, PhD
Roger Fillingim, PhD
Gerald F. Gebhart, PhD
Jennifer Haythornthwaite, PhD
Keela Herr, PhD RN
Charles Inturrisi, PhD
Robert Jamison, PhD
Jianren Mao, MD PhD
Gayle Page, DNSc RN
Kathleen Sluka, PhD
George Wilcox, PhD
The
2008 grant application process will be
announced in May 2008.
Data
Blitz for Clinical and Basic Science Research:
Request for Submissions
APS
announces a request for submissions for
the Data Blitz for Clinical and Basic
Science Research, which will be held Wednesday,
May 7, from 7–9 pm in Tampa, FL,
as part of the 27th Annual Scientific
Meeting. Authors are encouraged to submit
"hot topics" for presentation
during the blitz; submissions from young
investigators and junior faculty are particularly
encouraged. Selected presenters will have
5 minutes to present data and 5 additional
minutes to answer questions. The blitz
will be moderated by a member of the APS
Scientific Program Committee.
To
submit your work for consideration, please
download the application,
complete all requested information, and
send it via e-mail to Jennifer
Reinard at jreinard@connect2amc.com.
All
applications are due by March 24, 2008.
Primary/presenting authors will be notified
of the Data Blitz Committee's selections
in early April. Blitz presenters will
be responsible for all costs associated
with travel to the annual meeting, including
meeting registration.
Important
note: Authors who will be presenting paper
or poster abstracts at the annual meeting
should not submit their work again
for the data blitz.
Journal
of Pain Highlights
The
following highlights summarize selected
articles from the January 2008
issue (volume 9, number 2).
Nabilone
for Treatment of Pain in Fibromyalgia
Ryan Quinlan Skrabek, Lena Galimova, Karen
Ethans, and Daryl Perry, University of
Manitoba Rehabilitation Hospital
Forty
subjects were selected for the nabilone
trial, which was conducted by researchers
at the University of Manitoba Rehabilitation
Hospital. They were divided into nabilone
and placebo groups and were treated for
4 weeks. The authors noted that this was
the first randomized, controlled-access
trial to evaluate nabilone for pain reduction
and quality-of-life improvement in fibromyalgia
patients. Nabilone is one of two oral
marijuana-based compounds, known as cannabinoids,
available in Canada and is approved to
treat nausea and vomiting during chemotherapy.
Results
of the Manitoba study showed that the
nabilone group had significant reductions
in pain and anxiety, measured by comparisons
with baseline scores on the visual analogue
scale for pain, the Fibromyalgia Impact
Questionnaire (FIQ), and the FIQ anxiety
score. The data led researchers to conclude
that nabilone has significant benefits
for pain relief and functional improvement
in fibromyalgia patients. Although the
improvement was significant, none of the
nabilone-treated subjects enjoyed complete
relief from their fibromyalgia symptoms.
Nabilone
was well tolerated by treated patients,
which the authors characterized as reassuring
because fibromyalgia patients are sensitive
to most medications and have difficulty
enduring side effects. The downside, however,
is cost. In Canada, the cost of a year's
supply of nabilone would be approximately
$4,000.
The
study concluded that the findings warrant
consideration of nabilone as an adjunct
to current medical management of fibromyalgia.
Interpreting
the Clinical Importance of Treatment Outcomes
in Chronic Pain Clinical Trials: IMMPACT
Recommendations
Robert A. Dworkin, Dennis Turk, et al.
A
prestigious group of 40 pain researchers
participated in a consensus meeting—Initiative
on Methods, Measurement, and Pain Assessment
in Clinical Trials (IMMPACT)—to provide
recommendations for interpreting treatment
outcomes in clinical trials for the efficacy
and effectiveness of chronic pain treatments.
The
meeting had two goals: (1) develop general
recommendations for determining clinically
important changes for chronic pain outcome
measures, and (2) propose provisional
benchmarks for identifying clinically
important changes in specific outcome
measures for chronic pain trials previously
recommended by the IMMPACT group.
Relatively
few studies have systematically asked
chronic pain patients to identify changes—both
improvements and deteriorations—in their
pain intensity. The group concluded that
such studies are important for pain research
and for determining what patients consider
important. IMMPACT previously recommended
four core outcome criteria: pain intensity,
physical functioning, emotional functioning,
and participant ratings of overall improvement.
In this article, the group suggested two
additional criteria be used: patient characteristics
(e.g., age, sex, education) and whether
changes in pain outcomes considered important
by patients vary by clinical condition
(i.e., low back pain vs. spinal injury
pain).
The
researchers believe that systematically
collecting and reporting the recommended
information will validate the proposed
benchmarks and provide more meaningful
comparisons of chronic pain treatments.
Pain
Medicine Highlights
The
following highlights summarize selected
articles from the November/December
2007 issue (volume 8, number 8).
Gender
Differences Among Patients with Fibromyalgia
Undergoing Multidisciplinary Pain Rehabilitation
W. Michael Hooten, MD,*
Cynthia O. Townsend, PhD,
and Paul A. Decker, MS
Departments of *Anesthesiology and Psychiatry
and Psychology, Division of Biostatistics,
Mayo Clinic College of Medicine, Rochester,
MN
This
study, conducted at a multidisciplinary
pain rehabilitation center at a tertiary
referral medical center, tested the hypothesis
that gender differences exist in physical
and emotional functioning among patients
with fibromyalgia undergoing multidisciplinary
pain rehabilitation.
Researchers
matched 33 men with fibromyalgia admitted
from January 2002–June 2005 with 33 women
with fibromyalgia for age, treatment dates,
and program completion status.
Before
and after a 3-week outpatient multidisciplinary
pain rehabilitation program, participants
were assessed using various outcome measures,
such as the Multidimensional Pain Inventory,
the Short Form-36 Health Status Questionnaire,
the Coping Strategies Questionnaire-Catastrophizing
subscale, and the Center for Epidemiologic
Studies-Depression scale. In addition,
researchers compared the numbers of patients
using opioids, nonsteroidal anti-inflammatory
drugs, and benzodiazepines before and
after treatment.
The
results showed that men had lower health
perception and more physical limitations,
and women had greater life interference
due to pain. Researchers observed that
"these results support the hypothesis
that pretreatment gender differences are
present among fibromyalgia patients undergoing
multidisciplinary pain rehabilitation
and posttreatment gender differences persist
despite improvements in physical and emotional
functioning."
Do
Users of Regularly Prescribed Opioids
Have Higher Rates of Substance Use Problems
Than Nonusers?
Mark J. Edlund, MD PhD,*
Mark Sullivan, MD PhD,
Diane Steffick, PhD,*
Katherine M. Harris, PhD,§
and Kenneth B. Wells, MD MPH
*Central
Arkansas Veterans Healthcare System, North
Little Rock, AR, Veterans; Department
of Psychiatry, College of Medicine, University
of Arkansas for Medical Sciences, Little
Rock, AR, Veterans; Department of
Psychiatry and Behavioral Sciences, University
of Washington, Seattle, WA; §RAND
Corporation, Arlington, VA; RAND Corporation,
Los Angeles, CA; Department
of Psychiatry and Behavioral Sciences,
University of California–Los Angeles,
Los Angeles, CA
When
prescribing patients opioids, clinicians
must be aware of potential drug abuse
problems and mediating mental health disorders.
In this study, researchers evaluated the
responses from a nationally representative
survey (N = 9,279) to determine
whether individuals who take prescribed
opioids for chronic noncancer pain exhibit
higher rates of any opioid misuse, any
problem opioid misuse, nonopioid illicit
drug use, nonopioid problem drug use,
or any problem alcohol use compared with
those who do not use prescribed opioids.
The survey assessed regular use of prescribed
opioids, substance use problems, mental
health disorders, physical health, pain,
and sociodemographics. Individuals using
prescribed opioids had higher rates of
opioid and nonopioid abuse problems compared
with nonusers of prescribed opioids; however,
the researchers believe these higher rates
are partially mediated by depressive and
anxiety disorders. Researchers concluded
that "it is not possible to assign
causal priority based on our cross-sectional
data, but our findings are more compatible
with mental disorders leading to substance
abuse among prescription opioid users
than prescription opioids themselves prompting
substance abuse iatrogenically."
APS
Elections Are Underway: Vote by March
14
Calling
all members; the APS national election
is now underway. Watch for your ballot
invitation via e-mail or U.S. postal mail.
Instructions and the Web address for the
online election ballot will be included
in these mailings.
This
year you will vote to elect a Secretary,
three Directors at Large, three Nominating
Committee Past Presidents, and four Nominating
Committee Members at Large. This year's
slate of candidates is outstanding and
represents the diversity and expertise
of APS's membership. What's more, voting
is easy and only takes a few minutes of
your time to complete. Your vote is important;
it's a way to influence the future of
your association. Don't miss out on that
opportunity.
If
you have questions about the elections
process, contact Marcia Cebula by phone
at 847/375-4843 or by e-mail at mcebula@connect2amc.com.
Voting will end March 14, 2008.
Foley
Award Nominations Due March 5
APS
sponsors the Kathleen M. Foley Journalist
Award to recognize excellence in reporting
pain-related topics. The award is designed
to honor the work of journalists whose
coverage of events, scientific discoveries,
patient care, issues, and policies contribute
to furthering public awareness and understanding
of pain and pain-related issues.
Nominations
from APS members for the Kathleen M. Foley
Journalist Award are due March 5. Please
email your nominations to Chuck Weber
at cpweber@weberpr.com.
In a short paragraph, your nomination
should state the name of the journalist
and publication and the title of the article
you believe merits consideration for the
award. A PDF of the article would be appreciated
but isn't necessary. Also, please give
a brief statement describing why you believe
the candidate should be considered.
A
Look Ahead: APS Annual Meeting
May 8–10, 2008
Tampa, FL
Register
online today!
Distinguished
Faculty
The APS 27th Annual Scientific Meeting
promises to offer lively interdisciplinary
exchanges among pain scientists and healthcare
professionals. The APS Scientific Planning
Committee, led by chair Tim Brennan, MD
PhD, has put together a program that appeals
to all disciplines. More than 130 distinguished
faculty will share their expertise
and research findings.
Online
registration is open. Register
today!
Corporate
Satellite Symposia
Eight corporate satellite symposia will
be offered in conjunction with the APS
Annual Scientific Meeting. These independently
sponsored, commercially supported symposia
are open to the registrants of the APS
27th Annual Scientific Meeting. The programs
have been reviewed by the APS Scientific
Program Committee and approved after determining
the topics to be presented are relevant
to the audience and complementary to the
official APS program. There is no fee
to attend these symposia, but preregistration
is required. Seating will be available
at no charge to those responding on a
first-come, first-served basis. Program
details are subject to change. Speakers
are subject to change. Please visit the
APS Web site for the most current information.
Thursday,
May 8
1–2:30 pm
State-of-the-Science:
Abuse-Deterrent Opioid Formulations
Nathaniel P. Katz, MD MS; Lynn R. Webster,
MD; Steven D. Passik, PhD
This session will summarize national data
and analyze recent research and local
data. Speakers will present data on types
of technology under development and the
available drug-specific research and discuss
the benefits and limitations of these
technologies. Finally, presenters will
identify patient populations for whom
these technologies will be most valuable
by assessing the types of aberrant behavior
addressed by such formulations and at
the same time recognizing populations
and behaviors for which they will likely
be less useful.
Supported by an educational grant from
Alpharma Pharmaceuticals LLC.
Traveling
Pain's Pathways: Basing Treatment Upon
the Underlying Neurobiology of Pain
B. Eliot Cole, MD MPA; David M. Simpson,
MD
Untreated pain has been shown to alter
neuronal function in key parts of the
brain, underscoring the importance of
early, effective treatment for pain to
mitigate potentially irreversible changes.
Ongoing pain research has uncovered fascinating
insights involving the interaction of
genetics, immune system, nervous system,
and skin, contributing to the experience
of pain. These insights have led to significant
therapeutic research involving the manipulation
of these natural processes to produce
new, more effective pain-reducing therapies.
Recognized experts in the field of pain
management will facilitate this highly
interactive activity using evidence-based
presentations, results from clinical trials,
and case study discussions to link advances
in the current understanding about the
neurobiology of pain and advances in the
diagnosis and treatment of pain. Participants
will also benefit from question-and-answer
sessions. Clinicians attending this symposium
will be able to appropriately prescribe
novel treatments minimizing side effects
by better targeting the body's specific
pain-fighting mechanisms. Pre- and post-activity
surveys will be conducted to elicit changes
in knowledge, skills, attitudes, and behaviors
in clinical practice.
Supported by an educational grant from
Eli Lilly and Company.
Friday,
May 9
6:45–8:15 am
Optimizing
Treatment Outcomes in Peripheral Neuropathic
Pain
Robert H. Dworkin, PhD; Miroslav Misha
Backonja, MD; Mark Steven Wallace, MD
Peripheral neuropathic pain presents a
diagnostic and treatment challenge for
healthcare professionals. In many cases,
a patient with a preexisting condition
presents with pain, the origin of which
may be neuropathic, nociceptive, or of
mixed etiology. In contrast to other sources
of pain, pain of neuropathic origin derives
from direct damage to the central or peripheral
nervous system. An accurate diagnosis,
though essential for effective treatment
of neuropathic pain, is often difficult
to achieve because of the subtle differences
in symptom presentation associated with
the different forms of pain. Further complicating
matters is the wide array of treatment
options for neuropathic pain as well as
treatments a patient may be receiving
for the underlying cause of such pain.
Optimizing outcomes for patients with
neuropathic pain requires a precise understanding
of diagnostic factors and the knowledge
of how and when to use the various treatment
options available for such patients. A
review of established treatment guidelines
will illustrate how a multidisciplinary
approach can further improve overall treatment
outcomes in patients with neuropathic
pain.
Supported by an educational grant from
NeurogesX, Inc.
Treatment
Strategies for Patients Not Responding
to Increased Doses of Opioids: An Analgesic
Roadmap for Clinicians
Charles Argoff, MD; Oscar de Leon-Casasola,
MD; Robert J. Gatchel, PhD ABPP
Clinicians treating chronic noncancer
pain patients are often faced with the
problem of inadequate response despite
escalating doses of opioids. Numerous
approaches have to be considered in these
cases, including the possibility of an
underlying neuropathic pain condition,
a case of genetic variation in the mu-opioid
receptor affecting the response, a possibility
of misuse or diversion, a possibility
of hyperalgesia, and so on. Through a
discussion of possible approaches to this
problem, the multidisciplinary panel in
this program will provide a practical
roadmap to clinicians for improving practice
and patient outcomes. Possible causes
of a lack of response to other analgesic
agents will be discussed as well. Supported
by an educational grant from Endo Pharmaceuticals
Inc.
12:30–2
pm
Multidrug
Therapy for Chronic Pain: Scientific and
Clinical Considerations
Paul J. Christo, MD; Charles E. Argoff,
MD; Tony L. Yaksh, PhD; Ian Gilron, MD
This program is designed to provide a
comprehensive review of the rationale
and evidence base supporting the use of
multidrug therapy for the treatment of
patients with chronic pain. The molecular,
cellular, and physiological mechanisms
of chronic pain and their practical considerations
for assessment and treatment will be discussed.
Of central importance will be current
and emerging strategies for developing
individualized, multidrug therapeutic
plans based, in part, on the etiology,
psychosocial comorbidities, and temporal
characteristics of the chronic pain state.
Supported by an educational grant from
Cephalon, Inc.
Fibromyalgia
Fundamentals for the Practitioner
Lesley M. Arnold, MD; David A. Williams,
PhD
Recently, there has been substantial progress
toward a better understanding of the complex
pathophysiologic and genetic mechanisms
underlying fibromyalgia. Although the
condition has gained acceptance as a heterogeneous
chronic pain syndrome, treatment advances
have led to the first FDA approval of
any drug indicated for use in patients
with fibromyalgia. Nevertheless, gaps
in knowledge persist and optimal management
strategies remain uncertain. This program
encompasses a review of the latest evidence
regarding the etiology and treatment of
fibromyalgia. A combination of didactic
and interactive case-based educational
methods are employed to provide clinicians
with expert guidance in diagnostic strategies
and treatment plans.
Supported by an educational grant from
Pfizer Inc.
6:30–8:30
pm
Misuse
and Abuse of Prescription Pain Medications:
Profiling the Effects of Pain Medications
and Minimizing Abuse, Misuse, and Diversion
of Combination Opioids
Doug Gourlay, MD; Herbert Kleber, MD;
James Zacny, PhD
This program is intended for those healthcare
professionals involved in pain management
and addiction, including physicians, nurses,
psychologists, and pharmacists. The program
will provide the most recent educational
information regarding the effectiveness
of current treatment options in pain management,
focusing on the importance of quality-of-life
factors during treatment as well as emerging
technologies that help address unmet needs
in pain management. The physiological
and psychological effects, as well as
responsible prescribing and education
around safeguarding and discarding prescription
pain medication, will also be addressed.
The first presentation will examine best
practices for minimizing and treating
prescription pain medication misuse and
abuse with an emphasis on teen abuse.
The second presentation will discuss profiling
the physiological and psychological effects
of prescription pain medications in recreational
and non-drug-abusing volunteers. The final
presentation will review the emerging
strategies in pain management to help
improve treatment outcomes in patients
with acute or chronic pain. A better understanding
of the current issues surrounding effective
pain management is required to help provide
patients who suffer from acute or chronic
pain with the most beneficial treatment
outcomes.
Supported by an educational grant from
Abbott Laboratories.
Saturday,
May 10
Noon–1:30 pm
Clinical
and Pharmacologic Perspectives on Opioid
Use: Evidence-Based Strategies for Risk
Assessment and Attenuation
Paul Christo, MD MBA; Robert N. Jamison,
PhD; Barry Eliot Cole, MD MPA; Steven
Passik, PhD
This symposium will present current perspectives
on pharmacologic and patient behavioral
factors contributing to the risk of opioid
abuse, misuse, and diversion. Pharmacokinetic
and pharmacodynamic characteristics that
may contribute to the potential for abuse
and misuse of various opioid formulations
will be discussed, as will the psychological
factors that put patients at increased
risk. Moreover, methods for assessing
individual patient risk as well as behavioral
and pharmacologic strategies for reducing
these risks in clinical practice will
be reviewed.
Supported by an educational grant from
King Pharmaceuticals, Inc.
Tampa
Tampa Bay is a vibrant waterfront area
on Florida's beautiful west coast
that offers a unique blend of urban excitement
in a natural surrounding. Although it
was originally the name of a body of water,
Tampa Bay has come to represent the region
comprising many distinct communities connected
by the bay's waters. From the distinct
Latin roots of Tampa's historic Ybor City
and the Greek history of Tarpon Springs
to the thrills of Busch Gardens and the
many fascinating museums, you'll have
plenty of exciting attractions and communities
to explore.
From
flambé to flan, Tampa Bay's multinational
kitchen magicians work
wonders with fresh seafood and locally
grown produce. The dining scene in Tampa
Bay is among the most diverse and distinctive
in Florida. From the waterfront bistros
serving fresh seafood to the Spanish dishes
served by families who own and operate
their own cafes, the quest for a memorable
meal ends here. Every type of food and
every sort of atmosphere is offered on
the local menu.
From
land or water, observe an abundance of
birds in their natural habitats. Guided
waterfront cruises offer close-up views
of playful dolphins. Watch as fine cigars
are hand-rolled in Ybor City. Ybor City's
entertainment district, with more than
60 restaurants, bars, and nightclubs,
draws up to 30,000 people on weekend nights.
Tampa
Bay is a golfer's paradise, home to dozens
of golf courses and host to major golfing
events like the senior Champions Tour
Outback Steakhouse Pro-Am. Try your luck
year round at any one of their challenging
courses, or sharpen your skills at the
Arnold Palmer Golf Academy or Ben Sutton
School of Golf. Don't have a tee time?
Don't worry. There are services providing
last minute tee times at their finest
courses.
Need
more information? Visit the following
Web sites:
http://www.visittampabay.com/
http://www.tampaguide.com/
http://tampabay.citysearch.com/
http://www.tampabaymetro.com/
The
APS Annual Meeting will take place at
the Tampa Convention Center.
Hotels
APS has secured a limited number of sleeping
rooms at a special rate at the Tampa Marriott
Waterside Hotel & Marina and Embassy
Suites Downtown Tampa Convention Center.
Reservations
can be made online, by fax, or by mail
using the APS
housing form.
Young
Investigator Travel Support Application
Deadline Is Rapidly Approaching
APS
will again offer Young Investigator Awards
for travel to the 2008 meeting. Funding
awards are available to individuals presenting
paper or poster abstracts at the meeting,
May 8–10, 2008, in Tampa, FL. Applicants
may be from any research training background
(basic or clinical science, psychology,
medicine, or biostatistics) and may be
at any level in training, including students,
residents, predoctoral trainees, postdoctoral
fellows, or those who have completed their
postdoctoral training within the last
3 years. All applicants must be members
of APS.
The
Young Investigator Travel Stipend application
is available on the APS Web site at www.ampainsoc.org/meeting/annual_08/yits.htm.
Applications must be completed online
by February 29, 2008. If you have difficulty
completing the application, contact APS
at 847/375-4715. Applications will be
reviewed by the APS Scientific Program
Planning Committee, and stipends will
be awarded by March 14, 2008. Notifications
will be sent to all applicants after March
14. All eligible young investigators will
receive their travel grants at the annual
meeting.
The
APS travel stipend program is made possible
through educational grants and an allocation
of APS operating funds.
JAMA
Reports on Trends in Opioid Prescribing
for Patients Seeking Care in Emergency
Departments
A
recent study
in JAMA explored the effects that
national quality improvement initiatives
implemented in the late 1990s have had
on the prescribing of opioids for treatment
of pain in emergency departments. In particular,
the study examined whether differential
opioid prescribing by race/ethnicity has
decreased since 2000. The results showed
that overall opioid prescribing for patients
making a pain-related visit to the emergency
department has increased, but differences
in opioid prescribing by race/ethnicity
have not diminished.
Volunteer
Spotlight: Robert Yezierski, PhD
Robert
Yezierski, PhD, is a professor in the
departments of orthodontics
and neuroscience at the University of
Florida, and, as director of a postdoctoral
training program, spends a lot of time
thinking about the next generation—of
pain researchers, that is.
"It's
critical that our students are trained
properly to ensure there will be a well-equipped
work force of pain researchers and clinicians
that continues to develop and implement
new strategies of pain management,"
said Yezierski. "Also, there is growing
concern in the pain community that the
future of pain research may be in jeopardy
because the pipeline of new trainees is
not as plentiful as it was 10 years ago."
Citing
rapidly escalating demand for pain management
as the well-documented national aging
trend continues, Yezierski believes that
APS should be actively involved in recruiting
and developing the next generation of
pain researchers and clinicians. "Training
programs in the next decade need to teach
the vision of the future and not dwell
on past traditions. APS can be a strong
force in making that happen."
To
help APS move ahead in this direction,
Yezierski became a section editor of the
APS Bulletin, focusing on education
and training. "Together, physicians
and researchers must get involved in determining
pain research priorities. Our job as researchers
will be to make physicians aware that
they need to be part of the discussion
of identifying the important clinical
questions and furthering opportunities
for translational research," he explained.
Yezierski added that there is a critical
need to expand translational research
to help close the gap between what has
been learned about pain in the laboratory
and what is applied clinically.
"To
meet future needs in the field of pain,
it will be important to emphasize multidisciplinary
research strategies, and it will be critical
to translate findings into effective pain
management strategies at the bedside,"
Yezierski said.
A
member since 1988, Yezierski joined APS
while teaching at the University of Mississippi.
He was attracted to APS because he wanted
to become more involved in the pain care
community and benefit from the organization's
educational resources. "As a basic
scientist interested in studying pain
pathways, the APS Annual Meeting was a
vehicle for me to learn about the clinical
side of pain research," he recalled.
Through the years, Yezierski has periodically
served on the Scientific Program Committee,
made plenary session presentations, and
chaired panels at the annual meeting.
This
year in Tampa, Yezierski will participate
in a symposium titled "Effects of
Aging and Comorbidity on Pain Processing:
Clinical and Preclinical Studies."
The session will explore how aging affects
biological systems that influence pain
responses in an effort to better understand
pain mechanisms in the elderly and the
implications for new treatment strategies.
"The question of how advancing age
influences biological systems underlying
the pain experience may be the next major
challenge in the field of pain research,"
said Yezierski. "We need to understand
the biological variables responsible for
changing pain sensitivities as people
age."
Yezierski
is currently the director of the Comprehensive
Center for Pain Research and professor
of orthodontics, neuroscience, and anesthesiology
at the University of Florida and also
serves as president of the Florida Pain
Initiative.
IASP
Collaborative Research Grants
The
International Association for the Study
of Pain (IASP) is pleased to announce
a new grants program, IASP Collaborative
Research Grants, the first of which was
awarded in 2001. The purpose of these
grants is to encourage and support collaborative
research between two or more research
groups located in different countries.
The grants are intended to foster multidisciplinary
and international collaborations. Priority
will be given to collaborations between
basic science and clinical research groups.
The grants will cover, in full or in part,
the cost of travel and accommodation for
investigators of one group who work in
another of the collaborating laboratories.
Evidence must be provided that the costs
of the actual research can be covered
with other funds. The maximum grant awarded
will be $15,000. For more information,
please click
here.
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